LIN28B is an upstream regulator of BCL11A. Western blot analyses with protein extracts from empty vector control (C) versus LIN28B-OE (OE) cells (A-B), or BCL11A knockdown (KD) cells (C-D). The blots were probed with anti-LIN28B, and anti-BCL11A as labeled at the left of each band pair. An anti-β-actin probe was used as a loading control.