Phenotypic analysis of CNTRL-FGFR1 transduced and transplanted mice. (A) Comparison of splenic weight between leukemic and normal mice. (B) Comparison of survival from 3 chimeric BM transduction and transplanted mouse models. (C) Flow cytometric analysis (see “Methods”) of cells in BM, PB, SP, and thymus (Thy) from 2 mice with T-LBL shows a CD4⁺CD8⁺ phenotype. (D) Flow cytometry analysis shows that cells from a representative mouse that developed AML have a B220⁺Gr1⁺Mac1⁺ immunophenotype in both GFP⁺ and GFP⁻ cell populations.