Leukocyte dynamics in response to plerixafor in WHIM syndrome patients are durable over time. For each panel, the leukocyte subset indicated to the left of the corresponding row was measured immediately before and every 3 hours after a dose for 9 hours on the dates indicated and color-coded according to the scheme at the right of the figure. Patients were treated with plerixafor 0.1 to 0.2 mg/kg twice per day for the entire 6-month period of study. Data for each patient are arranged in columns and identified at the top. Horizontal dotted lines indicate the average baseline values before starting treatment. Note that baseline values shown for P3 correspond to P3 (b) in Figure 1.