Expression profiling reveals Myb-p300–regulated genes important for AML1-ETO–mediated transformation. (A-D). Venn diagrams and key below showing gene numbers and overlaps between gene sets I, II, III, and IV as defined in the text and supplemental Table 2, genes identified as binding c-Myb by chromatin immunoprecipitation and as Myb targets in Zhao et al,⁴¹  and genes affected by c-Myb short hairpin RNA knockdown in an MLL-AF9 leukemia model²¹  (supplemental Table 3). (E) Expression levels (heatmap) of a subset of the 58 genes in (A) regulated by AML1-ETO9a in WT but not in Boo cells, and their membership in c-Myb-related gene sets (blue side bar).