Figure 6
![Figure 6. CD16xCD33 BiKE consistently enhances NK cell function at all disease stages. The percent of CD56+/CD3− MDS-NK cells (A), total CD33+ cells (B), and MDS-MDSC (C) of the all-cell fraction was stratified according to their respective FAB classification and IPSS karyotype groups. (D-E) CD16xCD33 BiKE-induced MDS-NK cell functions (degranulation [CD107a], intracellular TNF-α and IFN-γ production) in the absence of HL-60 targets (D) and in the presence of HL-60 targets (E) were stratified according to their respective FAB classification and IPSS karyotype groups. The y-axes of graphs in panels D and E represent the percent of NK cells positive for each function listed in the graph legend.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/123/19/10.1182_blood-2013-10-533398/4/3016f6.jpeg?Expires=1735524733&Signature=nn9wEfBYYohzXcgLHH4m3122IGHRoGPQF7d4WqNknbkiW-H1DJlPYtaZiG3i1ITZthOppbZGxYxcfZ~E5dI6C~DmQx--GE9kjAXM4p3MunDDt2AcOHgLDst1kdo7PHiIBpb50RxrNxGnHZmUGFWqYkTbIKSZ0A4IRen-KMKVqKILvvN-chPU3K2KZM0gGImlnLre2cfwqe3qrkwuqpm8VhUQKz76ZnfD5aoZ9CUVpCDQlqZD9lcprKSaYFrPQqIciyrbLFRCCK93xqHtyy55IOPv2~VJ5~3lrghS2Y~hZpearrgUv2XtHsrN0CBxKHCWV53-eqIZnxZEKt3GgUUg0g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CD16xCD33 BiKE consistently enhances NK cell function at all disease stages. The percent of CD56+/CD3− MDS-NK cells (A), total CD33+ cells (B), and MDS-MDSC (C) of the all-cell fraction was stratified according to their respective FAB classification and IPSS karyotype groups. (D-E) CD16xCD33 BiKE-induced MDS-NK cell functions (degranulation [CD107a], intracellular TNF-α and IFN-γ production) in the absence of HL-60 targets (D) and in the presence of HL-60 targets (E) were stratified according to their respective FAB classification and IPSS karyotype groups. The y-axes of graphs in panels D and E represent the percent of NK cells positive for each function listed in the graph legend.
