Association between reduced chemotaxis and chemotactic accuracy with increasing age with preserved chemokinesis. Migratory chemotaxis, chemotactic index, and chemokinesis were measured in healthy subjects aged 21 to 89 years of age (n = 70). Linear regression identified an age-associated reduction in (A) neutrophil chemotaxis (R² = –0.4750, F = 56.99, P < .0001) and (B) chemotactic index (R² = –0.5399, F = 73.94, P < .0001) with increasing age. Age did not affect (C) neutrophil chemokinesis (R² = 0.004596, F = 0.2909, P = .5915).