Distinct expression patterns of DNMTs and potential DNA demethylases in hematopoietic cells. (A) Heatmap and clustering based on transcript levels of DNA methyltransferases and putative DNA demethylases showing gene expression levels from low (blue) to high (yellow) (see color key). The heatmaps were constructed using log10-transformed TPM values from CAGE data. For hematopoietic progenitors, individual samples are included because they were isolated based on different surface markers. For other cell types, replicate averages were used. (B-E) Average expression levels (TPM) of DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) and potential DNA demethylases (GADD45A, B, and G) are shown in hematopoietic cell types. Dotted line represents the threshold of 10 TPM, above which we considered expression to be significant.
