DNA methylation is reduced when MPO, ELA2, CST7, and PRTN3 expression increases. Transcription and DNA methylation levels of MPO, ELA2, CST7, and PRTN3. (A) Transcription levels measured with microarray analysis. The boxplots show the signals of all 5 replicates (arbitrary units). (B) Transcription levels measured with CAGE analysis (TPM). Mean expression of biological duplicates including tags over the entire gene normalized to the population with highest expression. (C) DNA methylation changes in MPO, ELA2, CST7, and PRTN3. The plot displays the change in β-value of all DMSs identified in each gene (from 1500 bp upstream of TSS to the end of the 3′UTR). Each dot represents 1 DMS.