Figure 2
Figure 2. Impaired thrombus formation in Bambi-deficient mice after FeCl3 injury in vivo. (A-B) Mesenteric arterioles were injured with FeCl3 and adhesion and thrombus formation of fluorescently labeled platelets was followed by intravital microscopy. (A) Representative images of thrombus formation at indicated times after removal of the filter paper. Scale bar represents 50 µm. A white asterisk indicates occlusion of the vessel for the wild-type mouse. (B) Bambi+/− and Bambi−/− mice displayed a delayed vascular occlusion compared with Bambi+/+ littermates. Each symbol represents 1 animal. Horizontal lines intersecting data sets represent the mean. Statistical analysis was performed using ANOVA (Kruskal-Wallis). **P < .01.

Impaired thrombus formation in Bambi-deficient mice after FeCl3 injury in vivo. (A-B) Mesenteric arterioles were injured with FeCl3 and adhesion and thrombus formation of fluorescently labeled platelets was followed by intravital microscopy. (A) Representative images of thrombus formation at indicated times after removal of the filter paper. Scale bar represents 50 µm. A white asterisk indicates occlusion of the vessel for the wild-type mouse. (B) Bambi+/− and Bambi−/− mice displayed a delayed vascular occlusion compared with Bambi+/+ littermates. Each symbol represents 1 animal. Horizontal lines intersecting data sets represent the mean. Statistical analysis was performed using ANOVA (Kruskal-Wallis). **P < .01.

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