Specific DNA-methylation and gene expression patterns for patient samples from cluster 11. Differential expressed and DNA-methylation genes in patient samples from cluster 11 compared with all other AMLs are indicated with different colored dots. The colors depict the gene expression and DNA-methylation status, ie, the right upper corner represents genes that are hypomethylated and overexpressed (green dots). Many of these genes encode for proteins involved in erythroid development or function (detailed results are depicted in supplemental Table 7).