Effect of c-Myc inhibition on NKG2D ligands expression. (A) Flow cytometric analysis for the expression of ULBP1/2/3 for resistant leukemia cells after specific inhibition of c-Myc using 10058-F4, and inhibition of ERK and AKT activation using PD98059 and MK-2206, respectively, after 24 hours of treatment. Data are representative of at least 3 experiments. (B) Real-time quantitative reverse-transcription PCR for the mRNA expression levels of ULBP1/2/3, transcripts in leukemia cells after 24 hours of treatment with c-Myc, ERK, or AKT inhibitor.