The expression ofL-selectin and PSGL-1 are decreased on c-Kit⁺Lin^–BCR-ABL1⁺stem/progenitor cells. Flow cytometric analysis of the normalized expression level of adhesion molecules (x-axis) on (left) BM, (center) PB, and (right) spleen cells from a mouse with BCR-ABL1–induced CML-like disease (black lines), gated on c-Kit⁺Lin^–GFP⁺ cells, vs normal c-Kit⁺Lin^– BM cells (gray): (A) α₄-integrin, (B) α₅-integrin, (C) α₄β₇-integrin, (D) LFA-1 (α_Lβ₂), (E) CXCR4, (F) PSGL-1, and (G) L-selectin. Staining with PE-conjugated isotype antibody is indicated by the dotted histograms in the BM samples. Data are representative of 3 independent experiments on mice euthanized 3 weeks after transplantation.