Combination of CSL362-mediated ADCC and TKI treatment further reduces CML but not normal CFUs. CP-CML (A) and normal CD34⁺ (B) (n = 3 each) cells were cultured with nilotinib at varying concentrations as indicated for 48 hours before overnight exposure to CSL362 (1 µg/mL) with or without allogeneic NK cells (E:T 1:1). Mean ± standard error of CFU colony numbers is shown. *P < .05; **P < .01; ***P < .001 (by unpaired Student t test).