Effect of antiplatelet agents added in vitro to samples from healthy volunteers on maximal platelet aggregation. (A) Dose-response curves obtained with Optimul in 10 healthy volunteers, presented as median and interquartile range. Open squares represent nontreated samples, the red triangles represent aspirin 100 µM–treated samples, and the green circles represent cangrelor 1 µM–treated samples in the same individuals. (B) Dose-response curves obtained with LTA in 10 healthy volunteers, presented as median and interquartile range. Open squares represent nontreated samples, the red triangles represent aspirin 100 µM–treated samples, and the green circles represent cangrelor 1 µM–treated samples in the same individuals.