Figure 4
Figure 4. Elavl1 regulates gata1 transcript levels. Shown are representative embryos following in situ hybridization for hematopoietic markers at the 5-somite (A-F) or 15-somite (G-L) stages in embryos that had been injected with 4 ng of control MO (left panels) or elavl1a Mo1 (right panels). Transcripts were analyzed for lmo2, scl, and gata1 as indicated, and embryos were flat-mounted, shown dorsal with anterior to the left. For each sample, n > 20, and the loss of gata1 transcripts (indicated by the arrows) was reproducible in independent experiments.

Elavl1 regulates gata1 transcript levels. Shown are representative embryos following in situ hybridization for hematopoietic markers at the 5-somite (A-F) or 15-somite (G-L) stages in embryos that had been injected with 4 ng of control MO (left panels) or elavl1a Mo1 (right panels). Transcripts were analyzed for lmo2, scl, and gata1 as indicated, and embryos were flat-mounted, shown dorsal with anterior to the left. For each sample, n > 20, and the loss of gata1 transcripts (indicated by the arrows) was reproducible in independent experiments.

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