GATA-1/Foxo3/Exosc8 coregulate genes important for erythroid maturation. (A) Classification of GATA-1– and Exosc8-regulated genes based on activation or repression. (B) Gene ontology analysis of GATA-1–activated, Exosc8-repressed genes. Redundant Gene Ontology categories were curated and removed. (C) Classification of Foxo3- and Exosc8-regulated genes based on activation or repression. (D) Gene ontology analysis of Foxo3-activated, Exosc8-repressed genes. Redundant Gene Ontology categories were curated and removed.