Cytokine release after CAR.GD2 stimulation. CAR.GD2 NKT cells were stimulated by CHLA255 NB cell line; supernatants were collected after 24 hours, and the concentrations of the indicated cytokines (A-F) were quantified using a Luminex assay. Plots represent combined data from 3 different donors. The maximal cytokine level in each experiment was used as 1, and data were normalized relative to the maximum in each experiment. Data are mean ± SD. *P < .05; **P < .01; ***P < .001, compared with Gz group, 1-way ANOVA with Bonferoni posttest analysis.