Adoptive transfer of CN-resistant EBV-CTLs induces reduction in tumor growth and improves survival of the mice despite the presence of ongoing immunosuppression. (A) Tumor volume (mm³) was decreased in tumor-bearing NSG mice adoptively transferred with CNA12-CTLs, CNA12-CTL +FK506, and eGFP-CTLs compared with the mice receiving eGFP-CTL + FK506 (n = 8). (B) The Kaplan-Meier tumor-related survival curve showed increased long-term survival of mice adoptively transferred with CNA12-CTLs in the presence of FK506 (P < .0001) compared with mice receiving eGFP-CTLs in the presence of immunosuppression (n = 7).