Cc2^−/− platelets display enhanced static adhesion on immobilized type I collagen. Time course of wild-type and Cc2^−/− platelet adhesion to either buffer control or type I collagen (50 µg/mL) in the absence of magnesium for 15, 30, 45, and 60 minutes at 37°C. Nonadherent platelets were removed and adherent platelets were measured as described in Materials and methods. The data represent 4 independent experiments. Note that Cc2^−/− platelets show a higher level of platelet adhesion to type I fibrillar collagen than wild-type platelets (^+/+) at all time points (*P < .05, **P < .01, ***P < .001; n = 4).