How I treat early-stage adult HL in 2014. Shown are the treatment strategies advocated by A.M.E. based on current clinical data. Based on available data, treatment should not be modified based on results of interim FDG-PET/CT; however, continued follow-up of ongoing studies, including results from studies examining intensification based on “positive” interim FDG-PET/CT, is needed. The treatment algorithms are separated by different early-stage subgroups: favorable, unfavorable (nonbulky), bulky, and older patients.