T cells resembling DNT can be detected among CD4⁺ and CD8⁺ T cells of ALPS patients. (A) Representative plots showing the proportions of CCR7-CD45RA⁺TEMRA, CD57⁺ and CD127⁻KLRG1⁻ T cells among ALPS versus control CD4⁺ T cells and CD8⁺ T cells. (B) Percentages of these populations in all studied ALPS patients (ALPS all), adult ALPS patients (ALPS >18 y) and controls (Con >18 y) with statistical comparison between all ALPS patients and adult controls. ns, not significant. **P < .01; ***P < .001.