Deletion of miR-142-3p caused trancriptome changes and activated interferon (IFN) γ signaling in zebrafish kidney myelopoiesis. (A) The difference and overlap between differential expressed genes (1.5-fold) in WKM after deletion of miR-142-3p and that in myelomonocytes. (B) The distribution of number of candidate target sites for miR-142-3p in codysregulated genes (twofold change) in WKM (without erythrocytes) and myelomonocytes after deletion of miR-142-3p. (C) Comparison of codysregulated IFN-γ signaling–related genes both in 142ab^−/− WKM (without erythrocytes) and 142ab^−/− myelomonocytes (1.5-fold). (D) qPCR analysis of expression of IFN-γ signaling–related genes in wild-type and 142ab^−/− myelomonocytes in zebrafish kidney. *P < .05 or **P < .01 vs wild-type; 2-tailed Student t test.