Figure 2
![Figure 2. Transcriptomic profile of EVI1-r AMLs. (A) Comparative analysis of expressed genes in EVI-r AMLs compared with AMLs without EVI1 rearrangements. Among expressed genes (ie, those with an average log10 expression ≥3, corresponding approximately to a reads per kilobase of transcript per million reads mapped [RPKM] of 0.1), the 20 most differentially expressed in EVI1-r AMLs are highlighted (solid rhombuses, also detailed in supplemental Table 7A). Color of dots shows the false discovery rate q-values. (B) Comparative analysis of MECOM, PREX2, MYCT1, VIP, and PAWR expression between EVI1-r AML, AML without EVI1 rearrangements, and normal CD34+ cord blood-derived cells. *P < .05, **P < .005, and ***P < .0005.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/125/1/10.1182_blood-2014-07-591529/4/140f2.jpeg?Expires=1735498549&Signature=hwm2EPOGcrWccLuRmBtpYCcHnlnA8fpapmK5~HQl0B8DRPr4L1XeKRQXvmxT2fodr-WX50lqAF8WZ1Dq7AI-nlouZyGmgaQPJc-e2gbOXlaGjLbI56u2zZA7LWd~p0hpxPEQT2VYQShMSfn5w~lSee35-5qO6aT5dHmPE~QtQZKsHx9Usl-ud--83xpkuPYFe-B0yL4tpzjCzJFAkct7kNUaTBxFdK8SfPGFP2xjDcaUSmLwuwl1x-8Hbi4cyCj8-kfiks~JOpCUQsiHzfHbNA1PwX0nE7sU4OF90IEZLsB8qcJ6KpR8jzSfRBy7uRVjdCKs2-yUzMWFM~olFA9XsQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Transcriptomic profile of EVI1-r AMLs. (A) Comparative analysis of expressed genes in EVI-r AMLs compared with AMLs without EVI1 rearrangements. Among expressed genes (ie, those with an average log10 expression ≥3, corresponding approximately to a reads per kilobase of transcript per million reads mapped [RPKM] of 0.1), the 20 most differentially expressed in EVI1-r AMLs are highlighted (solid rhombuses, also detailed in supplemental Table 7A). Color of dots shows the false discovery rate q-values. (B) Comparative analysis of MECOM, PREX2, MYCT1, VIP, and PAWR expression between EVI1-r AML, AML without EVI1 rearrangements, and normal CD34+ cord blood-derived cells. *P < .05, **P < .005, and ***P < .0005.
