Echinomycin treatment does not affect self-renewal of HSCs. BM cells from the recipients of competitive BMT were analyzed for composition of hematopoietic progenitors and stem cells at 29 weeks after transplantation. (A) Representative fluorescence-activated cell sorter profiles. Lin⁻CD45.1⁺ cells were analyzed for frequency of CD45.1⁺ hematopoietic progenitors and stem cells, including LSK, MP, MPP, LT-HSCs, and ST-HSCs. (B) Summary data of A. Data shown represent the means ± SD for 5 mice. These data have been repeated in 2 independent experiments.