New Investigator–initiated R01 principal investigator awards. Shown are the numbers of principal investigators applying to (PIs Apps, red) and funded by (PIs Awarded, blue) the NHLBI DBDR beginning in fiscal year (FY) 2000 and ending September 30, 2013 (FY 2013). Each funded principal investigator is included only in the first year during which he or she applied or was funded. This includes new and established principal investigators who were funded prior to FY 2000. The graph may be said to represent the “steady-state” of new or reentering hematologic PIs funded by the NHLBI DBDR over the represented time period.