Phenotypic characterization of CD2⁺CD25⁻ normal vs CD22^lowCD25⁺ activated bone marrow B lymphocytes. Flow cytometry analysis of (A) CD22⁺CD25⁻ vs CD22^lowCD25⁺ normal bone marrow B lymphocytes and (B) paired comparison of mean fluorescence intensity of CD22, CD27, CD200, and CD305 expression, as well as (C-D) their corresponding distribution within the naïve, IgM⁺, and IgM⁻ memory B-cell compartments.