Heatmap of miRNAs differentially expressed in patients who die of MCL. Hierarchical clustering of MCL samples from patients of the MCL2 cohort. The microarray-generated heatmap demonstrates differentially expressed miRNAs (adjusted P value <.05) in patients who died of MCL (cause-specific death) compared with patients who did not die of MCL. Seventeen miRNAs were found to be differentially expressed; of these, the 14 miRNAs shown at the top part of the figure (Up) had higher expression in the patients who died of MCL, whereas the 3 miRNAs shown in the bottom part (Down) had lower expression in the patients who died of MCL. Int., intermediate.