Platelet TSP1 contributes to thrombosis in injured arteries. (A) Schematic depicting the technique for generating mice with platelet-specific TSP1 deficiency. (B-D) Graphs representing (B) time to first thrombus formation (C), thrombus growth, and (D) mean occlusion time in FeCl₃-injured carotid arteries. Data are presented as mean ± standard error of the mean. N = 7 to 8 mice/group. *P < .05 compared with GPIbα/human IL4R transgenic mice reinfused with TSP1 deficient platelets.