Specific augmented expression of CCR2 on CANK cells derived from patients with TAP-2 deficiency. Surface expression levels of CCR2 on unactivated, CANK, and activated T cells derived from multiple blood samples obtained from healthy donors (representative staining for 1 of 23 healthy donors), the mother of patients A, B, and C with TAP-2 deficiency, and the patients themselves. Indicated values represent the percentages of cells positive for CCR2 of that total lymphocyte subset. Results are from 1 representative experiment of 3 experiments performed on lymphocytes and cell lines generated on 3 independent occasions from each donor.