VWFpp levels and VWFpp/VWF:Ag and FVIII:C/VWF:Ag ratios per type of VWD. (A) VWFpp levels and VWFpp/VWF:Ag and FVIII:C/VWF:Ag ratios are shown for type 1 and type 2 VWD patients. For a better presentation of the graphic VWFpp/VWF:Ag ratio, one type 1 VWD patient with both a high VWFpp/Ag ratio (33.7) and a FVIII:C/VWF:Ag ratio of 3.4 was omitted. (B) For all patients with type 2A, 2B, 2M, and 2N VWD, the VWFpp levels and the VWFpp/VWF:Ag and FVIII:C/VWF:Ag ratios are shown. The central horizontal line represents the median. The upper and lower horizontal lines show the 25% to 75% interquartile ranges. The dashed lines show the normal ranges (2.5th to 97.5th percentile) for VWFpp (range, 82 to 173 U/dL), for VWFpp/VWF:Ag ratio (range, 0.8 to 2.2), and for FVIII:C/VWF:Ag ratio (range, 0.6 to1.9).