RNA is detected in thrombi harvested from mice after FeCl₃-induced carotid artery injury. Representative thrombi harvested from the carotid artery of wild-type mice pretreated with (A,C) saline, (B) RNase, or (D) DNase. Before injury, mice were infused with an RNA- or DNA-specific fluorescent stain to identify RNA and DNA, respectively, within the thrombus. Thrombi were sectioned and subjected to immunofluorescence analysis using antibodies against HRG, fibrin, or platelets, or were stained with hematoxylin and eosin (H&E). Histologic sections were visualized with a ×100 objective lens fitted to an Olympus BX41 microscope equipped with a DP72 camera. Scale bars represent 100 μm.