Observed and projected burden of multiple myeloma in the US by sex and race/ethnicity. (A) Age-standardized rates per 100 000 person-years (2000 US Standard Population) by sex and race/ethnic group, as labeled. The dotted line separates the observed data for 1993 to 2010 from the 2011 to 2034 forecast periods. Data points show age-standardized rates based on 3-year age groups and calendar periods. Shaded regions show point-wise 95% confidence intervals. Forecasts are based on age-period-cohort model for each sex and race/ethnic group. (B) Number of new multiple myeloma cases per year in the US, 2011 to 2034, by sex and race/ethnic group, as labeled. (C-F) Distribution of multiple myeloma burden in the US among men (C-D) and women (E-F), by race/ethnicity; observed for 2011 to 2013 and projected for 2032 to 2034, respectively. Panels show pie charts sized in proportion to the total number of new cases per year. Slices show percentage distribution by race/ethnic group.