Genome-wide transcriptome profiling revealed a wide influence of mast cell-specific gene expression in the GATA2-deficient BMMCs. (A) Heat map showing color-coded expression levels of GATA factor-related genes in the GATA2-deficeint BMMCs. The RPKM values were obtained from 2 ΔCF/ΔCF BMMCs samples. Red indicates relatively high expression; blue indicates low expression; and white indicates intermediate expression in 4-OHT-treated (D4) vs untreated ΔCF/ΔCF BMMCs (D0), as indicated by the color bar. *Differentially expressed genes with a fold-change (D4/D0) <0.5 or >1.5. (B) The RPKM values of the RNA-seq samples prepared from 4-OHT-treated (black bars) and untreated (gray bars) BMMCs. (C) The results of the Q-PCR analyses of mast cell-specific genes in the ΔCF/ΔCF BMMCs. The PCR products amplified from ΔCF/ΔCF BMMCs on days 0, 5, and 10 of the 4-OHT treatment (D0, D5, and D10, respectively) are shown. N = 4.