Decreased miR-24 and increased VWF in diabetic mice. (A) qPCR analysis of tissue miR-24 levels (normalized to U6) in WT mice (n = 8-12). (B) Comparison of fasting blood glucose levels in diabetic mouse models (n = 6-12); ***P < .001. (C) qPCR analysis of miR-24 levels in DM mice lung (normalized to U6; n = 6-12); ****P < .0001; **P < .01; *P < .05. (D) qPCR analysis and comparison of miR-24 levels in in lean control and db/db mice lung and kidney (normalized to U6) and plasma (normalized to cel-miR-238 spike-in; n = 6∼8); ***P < .001. (E) qPCR analysis and comparison of VWF mRNA level in WT and STZ/HFD diabetic mice lung (normalized to glyceraldehyde-3-phosphate dehydrogenase [GAPDH]; n = 8-10); ****P < .0001. (F) ELISA analysis and comparison of VWF levels in WT and STZ/HFD diabetic mice plasma (n = 8-10); ***P < .001.