EpxCre/R-eYFP mice selectively mark eosinophils. (A) Flow-cytometric analysis of Siglec-F⁺ eosinophils in blood, spleen, and bone marrow from naive EpxCre/R-eYFP, EpxCre, and R-eYFP mice. Numbers indicate frequencies of gated cells. (B) Frequencies (upper graph) and total number (lower graph) of eosinophils in blood, bone marrow, lung, peritoneum, and spleen from naive EpxCre/R-eYFP (gray bars), EpxCre (black bars), and R-eYFP (white bars) mice. Bar graphs show the mean + SEM (n = 9) from 3 independent experiments. BL, blood; BM, bone marrow; LU, lung; PEC, peritoneal cavity; SP, spleen.