Outcome by randomization arm. (A) EFS by randomization arm. At 5 years, the EFS rate was estimated at 32.1% (95% CI, 24.0-40.4) in arm B vs 42.2% (95% CI, 33.5-50.6) in arm A (P = .13). (B) OS by randomization arm. At 5 years, the OS rate was estimated at 43.0% (95% CI, 33.9-51.7) in arm B vs 48.3% (95% CI, 39.2-56.8) in arm A (P = .37).