GATA3 SNP genotype and ALL genetic subtypes in AYAs. The allele frequency of rs3824662 varied substantially by ALL somatic genomic abnormalities, with the ALL risk allele underrepresented in hyperdiploid cases and more common in the Ph-like subtype. Numbers are based on the ALL cases included in the discovery GWAS (N = 308). The frequency of A allele at rs3824662 was 20% among unrelated non-ALL controls (MESA).