Time to event curves for patients in the phase 2 DRC study. (A) Overall survival (OS) according to age (≤65, 66 to 75, and 75 years). (B) WM-related and unrelated mortality. (C) OS per response category (including very good partial response [VGPR] category as per the revised response criteria published by Owen et al1 ). (D) Progression, and unrelated mortality without progression. CR, complete response; MR, minor response.