Figure 3
![Figure 3. PPXbd inhibits fibrin generation at low [TF]wall under venous conditions. Anticoagulated whole blood (CTI, 4 μg/mL) was treated with PPXbd (250 μg/mL) and was perfused over collagen or collagen/TF surface at 100 s−1 (constant Q). (A-C) Platelet deposition on collagen was unaffected by PPXbd despite the difference in [TF]wall. (D-F) Fibrin generation was inhibited by PPXbd only on collagen/low [TF]wall surface but not on collagen or collagen/high [TF]wall surface. *P < .05; **P < .01.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/126/12/10.1182_blood-2015-04-641472/4/1494f3.jpeg?Expires=1735507900&Signature=gfstVM97Nox1XapGyGRvaUi5hBjDnmuvz~O8FuLAzOp~mpbBA8-b679Px~yC7hS5Mm~MOdb0Q2OsQw4bNQJ7DysBM1zahC0V1Hx2PxSaCpun8Tw9Zfulfq~YRsKHnZ~yHUD7c0aWfR~4sXSzms-tOUcc3AR9dp9xILTpTB1B1L7wnF6Wr2IkDBtsDeVwJ5rpfkygD61wUdbGW1P8TLWb6~1l6FeosGWH2eYSyi2JbA-oQ5dndoaeLbUMPguS5f4hRzQQqvFOkyPcF0eHxhkY9PioqOXdyFkRNs3ywBSAbzcXLFKIXVKdV9M-4K--TLdBCQ44YatxaRUIePMBHVDUoA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
PPXbd inhibits fibrin generation at low [TF]wall under venous conditions. Anticoagulated whole blood (CTI, 4 μg/mL) was treated with PPXbd (250 μg/mL) and was perfused over collagen or collagen/TF surface at 100 s−1 (constant Q). (A-C) Platelet deposition on collagen was unaffected by PPXbd despite the difference in [TF]wall. (D-F) Fibrin generation was inhibited by PPXbd only on collagen/low [TF]wall surface but not on collagen or collagen/high [TF]wall surface. *P < .05; **P < .01.
