Adjusted OS according to baseline characteristics. Cox proportional hazard model of OS with age, gender, underlying disorder, WHO-PS, inhibitor concentration, and baseline FVIII activity as categorical covariates. Patterns were drawn according to (A) baseline FVIII (<1 IU/dL n = 47 vs ≥1 IU/dL n = 55, P < .05), (B) malignancy status (present n = 13 vs absent n = 89, P < .05), and (C) WHO-PS (≤2 n = 64 vs >2 n = 38, P < .01).