Characterization of the abnormal B-cell population in Hhex^−/Δ mice. (A) Flow cytometric analysis of the BM of Hhex^−/Δ mice showing gating of the “aberrant” B-cell (CD19⁺B220⁻) population and subsequent analysis of expression of Kit versus IgM, CD93, CD23, CD21, CD24 (HSA), Synd-1 (CD138), IL-7Rα (CD127), and CD43. Note that the top 5 plots and bottom 4 plots are from different mice of the same genotype. (B) Hierarchical clustering analysis of microarray data from CD19⁺B220⁻ B-cells from Hhex^−/Δ mice (“Aberrant B,” boxed) vs B- and T-lymphoid populations analyzed by the ImmGen Consortium.²³