Knockdown of MKL1 alters fibroblast morphology and migration. (A) Clinical photos showing skin scarring and hyperpigmentation after treating skin abscesses with antibiotics. (B) Migration of fibroblasts expressing SCR and MKL1 shRNA at 0, 9, and 18 hours. (C) Quantification of the area of migration observed in (B). (D) Confocal images of fibroblasts expressing SCR and MKL1 shRNA. Cells were stained with Alexa Fluor 647 phalloidin. White arrows indicate stress fibers. *P < .05.