One-year TRM in relation to median 3-IS level within the first 10 days after ASCT. (A) One-year TRM in patients with low 3-IS levels (≤6.9 µmol/mmol crea, n = 75) between days 0 and 10 after ASCT was significantly increased (P = .017) as compared with patients with high 3-IS levels (n = 55). (B) One-year OS in patients with low levels (≤6.9 µmol/mmol crea, n = 75) of 3-IS between days 0 and 10 after ASCT was significantly decreased (P = .05) as compared with patients with high 3-IS levels (n = 55).