VEGF-A increases chemokinesis of CD49d⁺ human neutrophils. Polar plots displaying the trajectories of (A) CD49d^– or (B) CD49d⁺ human neutrophils migrating in stable gradients of VEGF-A (from 4 independent trials). Gradients were formed with high concentration to the right side of the plots. (C) Neutrophils did not show chemotaxis in response to the VEGF-A gradient. Analysis of neutrophil migration by measuring (D) the average displacement, (E) the average track length, and (F) the average velocity per migrating neutrophil show that CD49d⁺ neutrophils display enhanced chemokinesis in the presence of VEGF-A. *P < .05.