Clinical courses after CBT in each group of CY/TBI and HDCA/CY/TBI. The cumulative incidence of major events after CBT, such as engraftment, GVHD, and infection, are summarized. In each event, HRs in the HDCA/CY/TBI group were analyzed in comparison with the CY/TBI group after being adjusted for confounding factors. HRs are shown by black dots, and 95% CI ranges are indicated by black bars. Engraftment of neutrophils and platelets was in favor of HDCA/CY/TBI. The incidence of grade II to IV aGVHD and cGVHD was significantly higher in the HDCA/CY/TBI group, but not grade III to IV aGVHD. Addition of HDCA did not cause any increase in the incidence of infection episodes (including bacteria, fungi such as Candia spp. and Aspergillus spp., and viruses such as CMV and human herpes virus-6) compared with the conventional CY/TBI regimen.