Bone marrow– or non–bone marrow–derived COMP in hemostasis and thrombosis. Chimeric mice were created by WT or COMP^−/− (recipients) mice crosstransplanted with bone marrow from WT or COMP^−/− mice (donors). (A-C) Tail-bleeding time (A), blood clotting time (B), and carotid artery occlusion time following FeCl₃ injury (C) in chimeric mice. (D) TT was measured in the platelet-free plasma isolated from chimeric mice. n = 6 for each group. *P < .05; BM, bone marrow; NS, not significant.