Figure 1
![Figure 1. CC-122 induces growth arrest and apoptosis in ABC- and GCB-DLBCL cell lines. (A) Multiple DLBCL cell lines were treated with dimethylsulfoxide (DMSO) and CC-122 (0.01-10 000 nM) for 5 days. Proliferation for all cell lines was determined using the 3H-thymidine incorporation method. Results of 3 independent experiments are shown (mean ± standard error of the mean [SEM]). (B) DLBCL cell lines were treated with DMSO, and CC-122 (0.1-10 μM) for 7 days, after which apoptosis was measured by Annexin V and To-Pro 3 flow cytometric analysis. Graphical representation of 2 independent experiments (mean ± SEM).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/126/6/10.1182_blood-2015-02-628669/4/779f1.jpeg?Expires=1736043508&Signature=CqNHVXc06ZtUQT~HdHzf9Vw8Hfzx9443d4MPMpWdY70VVteZ~tpEJA01WIm7SeF1vka~GvJxg8nqMGA-IEfxliWcSbN6eOP5mhrAE4P9cNQrLCkdVYeroSX8Yf0Xeq9C79RYEWceXXcGz~KkWc30NyZxwATS4EnTrQqG1MVQcuIrsnvs~8U477OTutNa2PzwbauwAzPnSqdbPYh1ICz7fPqGP-qg4LHPzsv2d9o8cMhiz5TCIywfhgy06TWvezlUse-xYeQnciZrjWm4REy2nrDFztcdbEevryZa0aiPNzRXpELfRv8HS310IwV3mfxyjWepTyX~ClTkj-v9FYfAAA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
CC-122 induces growth arrest and apoptosis in ABC- and GCB-DLBCL cell lines. (A) Multiple DLBCL cell lines were treated with dimethylsulfoxide (DMSO) and CC-122 (0.01-10 000 nM) for 5 days. Proliferation for all cell lines was determined using the 3H-thymidine incorporation method. Results of 3 independent experiments are shown (mean ± standard error of the mean [SEM]). (B) DLBCL cell lines were treated with DMSO, and CC-122 (0.1-10 μM) for 7 days, after which apoptosis was measured by Annexin V and To-Pro 3 flow cytometric analysis. Graphical representation of 2 independent experiments (mean ± SEM).
