H3K9me2 protects γ-globin gene promoter from LDB1/GATA-1/TAL1/LMO2 protein complex occupancy. (A) LDB1, (B) GATA-1, (C) TAL1, and (D) LMO2 protein occupancy at LCR HS sites, and γ-, δ-, and β-globin gene promoters in control and phase 2–treated cells at culture day 14. Error bars indicate SEM; n = 3 independent donors for each condition. Values are compared with the value for control. *P < .05 by Student t test.