Hematological analysis of the BM and spleen in BM transplanted EPCR^WT/WT and EPCR^R84A/R84A mice. EPCR^R84A/R84ABM/EPCR^WT/WT chimeric mice (R84A>WT) were generated by transplanting BM from EPCR^R84A/R84A mice into irradiated recipient EPCR^WT/WT mice. EPCR^WT/WTBM/EPCR^R84A/R84A chimeric mice (WT>R84A) were generated by transplanting BM from EPCR^WT/WT mice into recipient EPCR^R84A/R84A mice. Control mice were recipient EPCR^R84A/R84A mice transplanted with EPCR^R84A/R84A BM (R84A>R84A) and recipient EPCR^WT/WT mice transplanted with EPCR^WT/WT BM (WT>WT). Six months post-BM transplantation, mice were sacrificed and total cell counts of BM (A) and spleen (B) were performed. Splenic weight was assessed (C). Data represents the mean ± SE; *P < .05, **P < .01, ***P < .001; n > 5 per group.