Platelet contribution to neutrophil peripheral mobilization and recruitment to the skin during the cutaneous rpA reaction. (A) Comparison of the circulating neutrophil count in control wild-type, thrombocytopenic, and GPVI^−/− mice before and after induction of the rpA reaction. (B) Quantification and comparison of neutrophil recruitment as assessed by measurement of skin MPO content. # indicates a statistically significant increase (P < .05) in skin MPO content as compared with control spots from control wild-type mice. n = 6-12 mice per group. NS, not significant.